Comparison of the extratympanic electrocochleography in human and rabbit

  Electrocochleography (ECoG) records the electrophysiologic activity of the most peripheral part of the auditory system, the inner ear cochlea and the 8th nerve. Auditory evoked potentials being recorded are Cochlear Microphonic (CM) and Summating Potential (AP). In order to provide the proper background for laboratory research and introducing an ECoG curve of a model animal, it was decided to record the ECoG from rabbit. Rabbits of either sex weighting about 2 kg (n=25) were experimented upon. Evoked auditory potentials to clicks of 75 and 85 dB were analyzed off-line and compared with human data obtained from a clinical audiometry laboratory. The results are as followed: -SP/AP amplitude and latency showed no significant difference in either intensities, in rabbit. -SP and AP amplitude and latency were significantly greater in rabbit. -The ratio of SP/AP amplitude and latency in rabbit and human indicated no differences. -AP amplitude in 75 dB intensity was greater in the right ear compared with the left (p ≤0.05) however, in other cases, amplitude of waves was greater in the left ear (p ≤0.05).